ВЛИЯНИЕ ДЕПОЛЯРИЗАЦИИ МЕМБРАНЫ НЕЙРОНОВ СУПРАХИАЗМАТИЧЕСКОГО ЯДРА НА СПАЙКОВУЮ АКТИВНОСТЬ IN VITRO

A.N. Inyushkin; Инюшкин А.Н.; M.A. Tkacheva; Ткачева М.А.; A.A. Petrova; Петрова А.А.; T.V. Ryazantseva; Рязанцева Т.В.; A.V. Parfenova; Парфенова А.В.

doi:10.18287/2541-7525-2014-20-3-170-177

EFFECT OF MEMBRANE DEPOLARISATION OF SUPRACHIASMATIC NUCLEUS NEURONS ON SPIKE ACTIVITY IN VITRO

Authors: Inyushkin A.¹, Tkacheva M.¹, Petrova A.¹, Ryazantseva T.¹, Parfenova A.¹
Affiliations:
1. Samara State University
Issue: Vol 20, No 3 (2014)
Pages: 170-177
Section: Articles
URL: https://journals.ssau.ru/est/article/view/4582
DOI: https://doi.org/10.18287/2541-7525-2014-20-3-170-177
ID: 4582

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Abstract

The properties of spike activity of neurons of the suprachiasmatic nucleus during their membrane depolarisation in vitro are investigated on rat hypothalamic slices. Depolarisation of membrane caused an increase in activity of cells and a decrease in entropy log interspike interval distribution were used as a measure of spikes irregularity generation. Possible mechanisms of the eﬀects are discussed.