Analysis ofmulticomponent mixture on the example of the drug ”Pentalgin” bythe methods of TLC and IR-Fourier spectrometry
- Authors: Lobachev A.1, Red’kin N.1, Trifonova Y.1
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Affiliations:
- Samara State University
- Issue: Vol 21, No 3 (2015)
- Pages: 164-173
- Section: Articles
- URL: https://journals.ssau.ru/est/article/view/4500
- DOI: https://doi.org/10.18287/2541-7525-2015-21-3-164-173
- ID: 4500
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Abstract
The definition of a qualitative composition of multicomponent drugs ”Pen- talgin” and ”Pentalgin ICN” by TLC and IR-spectrometry is carried out. It is shown that using just TLC or just FT-IR spectrometry does not allow us to identify all the major components. It has been proposed an authentication scheme, which includes the steps of isolating of the test components, their sep- aration by TLC, followed by extraction of components and definition by FTIR spectrometry. The combination of these two techniques allows to separate and identify almost all the most important components of the mixture.
About the authors
A.L. Lobachev
Samara State University
Author for correspondence.
Email: morenov.sv@ssau.ru
N.A. Red’kin
Samara State University
Email: morenov.sv@ssau.ru
Yu.V. Trifonova
Samara State University
Email: morenov.sv@ssau.ru