Study of the derivatives of 1-adamantane carboxylic acid to induced plateletaggregation human in vitro


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Abstract

The study of condition of the system of hemoglobin, release of peptide com- pounds, and proteolytic activity of human erythrocytes under conditions of hy- perglycemia of varying degrees is carried out. The increase in the level of hy- perglycemia is accompanied by a decrease of affinity of hemoglobin to oxygen and the growth of level of metgemoglobin, the glycosylated hemoglobin level is increased in conditions of severe hyperglycemia. The level of formation of pep- tides in erythrocytes and the level of output of their cells is determined by the increase in trypsin-like activity in cytosol and increased membrane permeability of red blood cells.

About the authors

A.S. Gil’mutdinova

Самарский государственный университет

Author for correspondence.
Email: morenov.sv@ssau.ru

V.A. Ermokhin

Самарский государственный университет

Email: morenov.sv@ssau.ru

N.A. Klenova

Самарский государственный университет

Email: morenov.sv@ssau.ru

P.P. Purygin

Самарский государственный университет

Email: morenov.sv@ssau.ru

References


Copyright (c) 2017 А.С. Гильмутдинова, В.А. Ермохин, Н.А. Кленова, П.П. Пурыгин

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