GASTRIN-REALISING PEPTIDE - POTENTIAL PARTICIPANT INVOLVED IN THE BULBAR MECHANISMS OF THE REGULATION OF BREATHING

In the article we review the role of gastrin-realising peptide in the respiratory
control at the level of the medulla. The information concerning the distribution
of this neuropeptide and its receptors expression in the functionally-specific re
gions of the respiratory center is presented. We also review some data about
respiratory effects of related peptide bombesin. The effects of gastrin-realising
peptide microinjections into the nucleus tractus solitarii on the main parameters
of breathing pattern and the activity of inspiratory muscles are presented.