Assessing mechanical properties of tissue phantoms with non-contact optical coherence elastography and Michelson interferometric vibrometry
- Authors: Li J.1, Liu C.1, Schill A.1, Singh M.1, Nair A.1, Zakharov V.P.2, Larin K.V.1
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Affiliations:
- University of Houston
- Samara State Aerospace University
- Issue: Vol 1, No 4 (2015)
- Pages: 229-235
- Section: Articles
- URL: https://jbpe.ssau.ru/index.php/JBPE/article/view/2809
- ID: 2809
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Abstract
Purpose: Elastography is an emerging method for detecting the pathological changes in tissue biomechanical properties caused by various diseases. In this study, we have compared two methods of noncontact optical elastography for quantifying Young’s modulus of tissue-mimicking agar phantoms of various concentrations: a laser Michelson interferometric vibrometer and a phase-stabilized swept source optical coherence elastography system. Methods: The elasticity of the phantoms was estimated from the velocity of air-pulse induced elastic waves as measured by these two techniques. Results: The results show that both techniques were able to accurately assess the elasticity of the samples as compared to uniaxial mechanical compression testing. Conclusion: The laser Michelson interferometric vibrometer is significantly more cost-effective, but it cannot directly provide the elastic wave temporal profile, nor can it offer in-depth information.
About the authors
Jiasong Li
University of Houston
Email: songshan311@gmail.com
United States
Chih-Hao Liu
University of Houston
Email: uhliu1988@gmail.com
United States
Alexander Schill
University of Houston
Email: ASchill@Central.UH.EDU
United States
Manmohan Singh
University of Houston
Email: msingh@swbell.net
United States
Achuth Nair
University of Houston
Email: achuthg.md@gmail.com
United States
Valery P. Zakharov
Samara State Aerospace University
Email: zakharov@ssau.ru
Russian Federation
Kirill V. Larin
University of Houston
Author for correspondence.
Email: klarin@Central.UH.EDU
United States